Genetic testing for Methylation defects

Discover how your genetic makeup affects your body's ability to process essential nutrients and detoxify harmful substances. Our Genetic Methylation Screen Panel provides personalized insights to help you achieve optimal health and well-being.

What is Methylation?

Methylation is a crucial biochemical process in your body that influences everything from energy production and brain function to detoxification and DNA repair. When this process doesn't work properly, it can lead to various health issues, including fatigue, mood swings, and difficulty concentrating.

Why Take the Genetic Methylation Screen Panel?

Understanding your genetic variations can provide valuable insights into how your body handles essential processes. Our MethylDetox Profile helps identify specific genetic variations that might impact your health, allowing for a personalized approach to your wellness.

Benefits of the MethylDetox Profile

Cardiovascular Diseases e.g. hypertension, coronary artery disease, stroke 4-10
Neurological Disorders e.g. depression, dementia, Alzheimer’s disease, ADD/ADHD, ASD, chronic fatigue syndrome, migraine, insomnia 7, 10-17
Metabolic Conditions e.g. metabolic syndrome, diabetes mellitus, kidney diseases, reduced ability to metabolize medications, multiple chemical sensitivity 10, 18-21
Musculoskeletal Disorders e.g. osteoporosis 10, 22
Eye Diseases e.g. macular degeneration 23, 24
Cancer e.g. colorectal, breast, and others 1, 10, 25

How It Works

Schedule Your Appointment: Click below to set your consultation with our doctor to determine which testing is right for you.
Simple Sample Collection: Collection can be done at home or in a lab depending on which test is ordered.
Send It Back: Return your sample using the prepaid envelope.
Get Your Results: Receive a detailed report with personalized health insights and recommendations from the doctor.

Take Control of Your Health Today!

Ready to discover the key to your optimal health? Order your Genetic Methylation Screen Panel now and start your journey to a healthier, more vibrant life.

Call to schedule your test

What is Tested

MTHFR

The MTHFR gene’s purpose is to produce the important MTHFR enzyme in the body. This enzyme is an important part of maintaining optimal health. If the MTHFR gene has a variant, folate metabolism can be negatively impacted. Improper folate metabolism is implicated in many different diseases. 5, 6, 10, 26-29

MTR

MTR codes for the enzyme, methionine synthase (MS). MS converts homocysteine to methionine using methylated vitamin B12. variants in this gene significantly impact homocysteine metabolism, which can increase the risk for a number of chronic conditions such as cardiovascular diseases, metabolic and neurological conditions and certain cancers. 30

MTRR

The MTRR gene codes for the important enzyme, methionine synthase reductase (MSR). Methionine synthase reductase is required for the proper function of methionine synthase (see MTR). Both genes act together to convert homocysteine to methionine. variants can be involved with the development of cancers, Parkinson’s disease, depression, hypertension and many others. 31-36

COMT

COMT is the major gene involved in methylation. It plays an important role in a variety of disorders, including estrogen-induced cancers, Parkinson’s disease, depression, hypertension and many others. COMT is also necessary for maintaining the proper balance of neurotransmitters with SAMe obtained from methionine. Genetic variants in COMT can result in various neurological problems and has also been associated with Autism. 31-36

AHCY

AHCY is the only enzyme known to convert S-Adenosylhomocysteine (AdoHcy) to homocysteine. It is crucial that AHCY immediately converts AdoHcy to homocysteine and adenine in order to maintain optimal methylation potential. Studies show a link between variants in this gene with poor methylation potential and severe myopathies, developmental delays and hypermethioninemia.

Homocysteine

Homocysteine is an amino acid that is involved in maintaining the methionine cycle. Elevated homocysteine levels are well known risk factors for chronic disease, particularly cardiovascular, diabetes and neurodegenerative disorders 7, 10, 37